As a new drug packaging method, prefilling and sealing syringe is simple to use and easy to operate, which greatly reduces the dispensing process before drug use. Dosage errors are reduced because preinfusion syringes contain the full and precise absolute dosage, which is a novel device that combines the primary packaging of liquid preparations with the syringe.

Prefill the syringe

The pre-filling and sealing syringe is mainly composed of needle tube, rubber piston, push rod, cone head and helmet. The syringe module has good compatibility with drugs, and the syringe itself has good sealing performance, so drugs can be stored for a long time. The sealing of prefilling and sealing syringes is mainly controlled by the following points:

1. Adopt sealed components conforming to international standards;

2. In case of any change in the components of the sealing system or the sealing system, the impact on the sealing system shall be evaluated in a timely manner and the sealing integrity shall be re-verified if necessary;

3. The verification of sealing requirements shall meet the requirements of bacterial invasion test and saturated brine test;

4. In addition to the conventional experimental method, influence factor experiments and accelerated experiments should also be carried out to ensure that the sealing performance of the prefilling and sealing syringe can meet the user's requirements in the period of validity.